Matilda S's blog posts
Supporter stories New Years News
We greet the New Year with the sad news of the death of Gary Ablett, former Liverpool and Everton footballer who died of non-Hodgkin Lymphoma on New Year’s Day at the young age of 46.
Supporter stories More clinical trials will save more lives in the UK
Radio 4’s The Report recently examined the 2% decline in clinical trial activity in the UK, asking what effect the planned spending cuts will have on medical research in this country.
Supporter stories Treating childhood leukaemia in the 2000s
By 2000 around 80 percent of children were cured of the most common form of leukaemia, acute lymphoblastic leukaemia (ALL), and around 50 percent were being cured of acute myeloid leukaemia (AML). Remarkably, the drugs used in 2000 were not much different from those used in the 1970s, but research and clinical trials changed the way these drugs were administered with doses ‘individualised’ for each patient, and we were much better able to manage side-effects, reducing treatment related fatalities.
Supporter stories Treating childhood leukaemia in the 1990s
By the start of the 1990s scientists were beginning to understand more and more about how leukaemia develops in children. It was around this time that doctors firmly established the difference between childhood ALL, which is a distinct disease in children, and AML, which is a very similar disease in adults and children. This is why children with different forms of leukaemia do not respond to the same treatments.
Supporter stories Treating childhood leukaemia in the 1980s
By the start of the 1980s, more than 80 percent of children diagnosed with acute lymphoblastic leukaemia (ALL) were being recruited into the UKALL trials. This huge jump in recruitment accelerated the refinement of existing drugs and meant that these children were receiving the best available treatment.
Supporter stories Treating childhood leukaemia in the 1970s
During the 1970s our knowledge of genes and DNA greatly increased and scientists began to understand better how leukaemia develops and the way in which treatments could be improved. At this point around half of children being treated for leukaemia entered a sustained remission, though most of these were not cured and would later relapse. The other half still died quickly.