Myeloma TAP trials

Myeloma TAP trials

We have a clinical trial that is looking at treatment for people with certain gene changes in their myeloma cells, whose myeloma has come back or treatment has stopped working. 

Myeloma

Some people have gene changes in their myeloma cells, causing them to not respond well to standard chemotherapy as well as other treatments. This group of people are also more likely to see their myeloma return.

Bortezomib is one of the usual therapies for myeloma, and researchers think that adding another drug called buparlisib could help people with gene changes. 

We are supporting the BUBBLE trial that will be testing this drug combination.

BUBBLE trial

Chief investigator - Professor Kwee Yong, University College London
Myeloma
A phase Ib study of BKM120 with bortezomib in defined genetic subgroups of patients with relapsed or refractory multiple myeloma
Some people have gene changes in their myeloma cells, causing them to not respond well to standard chemotherapy as well as other treatments. This group of people are also more likely to see their myeloma return. There is a great need to develop new drugs for people with poor outcomes. We are supporting a clinical trial called BUBBLE, which is looking at a treatment for myeloma that has stopped responding to treatment, or has returned.